The CXCR3 antagonist NBI-74330 alleviates neuroimmune dysfunction by lowering pro-inflammatory mediator signaling in CD45+ cells of BTBR T+ Itpr3tf/J mice
IntroductionAutism Spectrum Disorder (ASD) is a neurodevelopmental condition that affects social interaction and communication and is often accompanied by stereotyped behaviors. This study examined the effects of the CXCR3 antagonist NBI-74330 on BTBR T+ Itpr3tf/J (BTBR), an autistic mouse model. Recent research suggests that NBI-74330, a CXCR3 antagonist, could have therapeutic benefits in…
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