Sleep-promoting and circadian interventions for prevention of postoperative delirium in adult surgical patients: a systematic review and meta-analysis
BackgroundSleep and circadian disruption may contribute to postoperative delirium (POD), but previous reviews often pooled sedative drugs, melatonergic agents, and broad delirium-prevention bundles.ObjectiveTo evaluate whether sleep-promoting and circadian interventions reduce POD in adult surgical patients.MethodsWe searched PubMed/MEDLINE, Embase, CENTRAL, Web of Science, Scopus, CINAHL, and…
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