Triple combination therapy trial for HR+/HER2− breast cancer halts early due to toxicity concerns

The Medical News ·
Health & Medicine United Kingdom

HR+/HER2− breast cancer constitutes approximately 65–75% of all breast cancer cases worldwide. Although CDK4/6 inhibitors have substantially extended progression-free survival (PFS), up to 60% of patients derive no clinical benefit from these agents, underscoring the urgent need for more effective therapeutic strategies.

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