Diagnostic and predictive value of structural and high-order functional brain topology in major depressive disorder
BackgroundConventional neuroimaging analyses for major depressive disorder (MDD) predominantly construct brain networks based solely on pairwise regional functional couplings. Accumulating microscale neuroscientific evidence highlights the essential role of higher-order interactions (HOIs, interactions among three or more brain nodes) in capturing the intricate spatiotemporal dynamics of the…
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