Smarter CAR-T cells could beat a deadly pediatric brain cancer
Scientists at UC San Francisco have engineered CAR-T cells that stay dormant until they reach the brain, where they switch on and destroy tumor cells. In mice, these CAR-T cells were able to clear diffuse midline glioma (DMG), a lethal form of childhood brain cancer that integrates into healthy tissue. The cells also had staying power. When scientists introduced another round of cancer several…
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