Comparative efficacy of naltrexone-accelerated versus sublingual buprenorphine in opioid withdrawal management and initiating injectable naltrexone treatment: study protocol for a randomized controlled trial
BackgroundExtended-release injectable naltrexone (XR-NTX), a long-acting opioid antagonist, is an effective relapse prevention strategy in the treatment of opioid use disorder (OUD). However, standard XR-NTX initiation requires completion of opioid withdrawal management and a 1–2 week opioid-free period. This interval is associated with heightened vulnerability to lapse and relapse, and many…
Read original article on Frontiers in Psychiatry | New and Recent Articles →