Ancient protein model shows early steps in energy metabolism

The Medical News · 2h ago

Researchers in Japan engineered ancestral nucleoside diphosphate kinase variants with restricted amino acid repertoires to explore alternative catalytic functions. One variant, Arc1-12KR, retained its protein fold despite lacking catalytic histidine and unexpectedly converted two ADP molecules into ATP and AMP. The findings reveal alternative catalytic potential in simplified proteins and offer…

Read original article on The Medical News →

Ancient protein model shows early steps in energy metabolism

Related news