Integrated bioinformatics analysis identifies a ubiquitination-related gene signature in schizophrenia with peripheral clinical validation
BackgroundDysregulation of the ubiquitin proteasome pathway is implicated in the pathogenesis of schizophrenia (SCZ). The objective of this study is to identify the dysregulation of the ubiquitin-proteasome pathway and the potential mechanisms associated with SCZ by comprehensive analysis using integrated GEO datasets.MethodsWe integrated three SCZ related datasets containing 1847…
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