Synthetic molecule improves mitochondrial function in ALS models and patient-derived stem cells

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Health & Medicine United Kingdom

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which motor neurons are gradually lost, leading to muscle weakness and, as the disease advances, difficulty breathing and swallowing. Existing medicines can slow disease progression to some extent, but no treatment has been established that fundamentally reverses the disease process. Mitochondrial dysfunction is…

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