The integrated bioenergetic-interoceptive model of schizophrenia-spectrum disorders
Schizophrenia has traditionally been conceptualized as a heterogeneous neurodevelopmental disorder involving neurotransmitter dysregulation, synaptic dysfunction, and large-scale brain network abnormalities. However, a growing body of convergent evidence indicates that schizophrenia is embedded in broader, system-level physiological dysregulation involving metabolic, immune, endocrine,…
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