Reduced serum levels of the pro-resolving lipid mediators resolvin D1 and lipoxin A4 in schizophrenia
Schizophrenia is increasingly conceptualized as a disorder of chronic, unresolved neuroinflammation, yet why the inflammatory burden fails to resolve remains unclear. Specialized pro-resolving lipid mediators—including resolvin D1 (RvD1) and lipoxin A4 (LXA4)—actively terminate inflammation but have rarely been examined in schizophrenia. Because no previous study has measured LXA4 in…
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