Plant essential oils as a novel therapeutic strategy for depression and anxiety: emerging evidence and mechanisms

Frontiers in Psychiatry | New and Recent Articles ·
Mind & Mental Health Switzerland

Depression and anxiety are major global mental health disorders that require safer and more accessible adjunctive interventions. This review uniquely integrates current evidence on plant essential oils in aromatherapy and identifies the cAMP–PKA–CREB pathway as a key mechanistic hub linking neurotransmitter regulation, HPA axis modulation, neuroinflammation, and neuroplasticity. Relevant animal,…

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