Prenatal genomics and autism: detectable susceptibility without validated individual-level prediction

Frontiers in Psychiatry | New and Recent Articles ·
Mind & Mental Health Switzerland

Autism spectrum disorder (ASD) is a behaviorally defined, biologically heterogeneous neurodevelopmental condition with high heritability, estimated at 0.83 (95% CI 0.79–0.87) in Swedish population data. Large-scale exome sequencing, copy-number variant analysis, and genome-wide association studies have implicated a growing number of genes and genomic loci in autism liability, and functional…

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