Inflammatory cytokines as predictors of therapeutic response to valproate in patients with comorbid alcohol use disorder and bipolar disorder
ObjectiveAlcohol use disorder (AUD) is a chronic condition commonly associated with bipolar disorder (BD). We previously reported that valproate (VPA) can decrease drinking in some patients with comorbid AUD/BD. Predictors of treatment response to VPA, however, are yet to be elucidated, and it is not possible to prospectively identify patients who may benefit from the course of VPA. Both…
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